Acute renal failure application
Acute kidney failure is caused by an inflammatory process in the kidney that can lead to loss of kidney function. Acute renal failure affects about 2 million patients annually in Europe, the USA and Japan, from which about 700,000 patients die.
The most common cause of acute renal failure in intensive – care patients is an inflammatory process that can lead to an acute tubule necrosis and loss of kidney function. which in general will be caused by renal ischemia ( hypotension, sepsis ), and toxic causes ( drugs or contrast medium) or a combination of both.
Acute renal failure is experienced in no less than 4% of hospital admissions and 40% of the intensive-care (mostly trauma) admissions. Depending on the severity and cause of the kidney damage, the percentage of deaths varies from 10% to 70%.
A preclinical study has demonstrated that the use of VANADIS® in acute renal failure, reduces reperfusion damage in the kidneys significantly.